Watson Talks a lot about ROMA

SO what is ROMA? Jonathan Sebat at Cold Spring Hrbor describes his research interest s here ... He says:

Large-scale differences in gene copy number, known as copy number polymorphisms (CNPs), are a significant source of human genetic variation. In contrast to DNA sequence variants such as SNPs and microsatellite repeats, CNPs have not been well characterized.....

...We hypothesize that submicroscopic alterations in gene dosage are underlying causes of diseases such as autism, schizophrenia, and Parkinson’s disease. We are currently investigating chromosomal variation in disease using a method for high-resolution analysis of DNA copy number called Representational Oligonucleotide Microarray Analysis (ROMA)

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So what are:
alterations in gene dosage

Representational Oligonucleotide Microarray Analysis

So there's a relevant paper on ROMA here [Representational Oligonucleotide Microarray Analysis: A High-Resolution Method to Detect Genome Copy Number Variation
Robert Lucito, John Healy, Joan Alexander, Andrew Reiner, Diane Esposito, Maoyen Chi, Linda Rodgers, Amy Brady, Jonathan Sebat, Jennifer Troge, Joseph A. West, Seth Rostan, Ken C.Q. Nguyen, Scott Powers, Kenneth Q. Ye, Adam Olshen, Ennapadam Venkatraman, Larry Norton,and Michael Wigler}

Emile; Or, On Education - Rousseau's Best?

Emile; Or, On Education by Jean-Jacques Rousseau written in 1762 was considered by him to be the “best and most important of all my writings” ... according to Wikipedia

is largely a philosophical treatise on the nature of man; it addresses political and philosophical questions regarding the individual’s relationship to society, in particular how the individual can retain what Rousseau saw as his natural goodness while participating in an inevitably corrupt society.

Kant was said to have stopped his daily routine in order to finish reading it.
[take a look at the Basic Book's version of Emile]

and then there's the Emile and Sophie matter ...

Descartes and the Hyperbolic Quest - Lense making

Descartes and the Hyperbolic Quest looks pretty interesting.


[full title =Descartes And The Hyperbolic Quest: Lens Making Machines And Their Significance In The Seventeenth Century (Transactions of the American Philosophical Society) by D. Graham Burnett}

goal of this post: Rene Bio Links ...

in Google Books

Immanuel Kant: Biographies

Manfred Kuehn's Kant: A Biography is touted as a new great addition to the topic.

Fifty Major Philosophers: A Reference Guide By Diané Collinson is also an interesting biographical resource.